Extracted proteins are exposed to the threat of degradation by proteases from the moment cells or tissues are lysed. Proteases present in the living cell are released from their regulated environment into the extract where they may freely degrade their targets, resulting in drastically reduced protein yield and sample
quality. Complex protein solutions are typically treated with a mixture of several protease inhibitors in order to preserve the native state of the proteins.
An aspartic acid protease inhibitor of pepsin, renin and cathepsin D. Also an inhibitor of the HIV protease. Not water soluble.